Cart
sales@molnova.com
GSK-3008348 hydrochloride
CAS No. 1629249-40-6
GSK-3008348 hydrochloride( GSK3008348 hydrochloride )
Catalog No. M12440 CAS No. 1629249-40-6
GSK-3008348 hydrochloride is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1430 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGSK-3008348 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionGSK-3008348 hydrochloride is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF).
-
DescriptionGSK-3008348 hydrochloride is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF). Cystic Fibrosis Phase 1 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsGSK3008348 hydrochloride
-
PathwayCell Cycle/DNA Damage
-
TargetIntegrin
-
RecptorIntegrin
-
Research AreaOther Indications
-
IndicationFibrosis
Chemical Information
-
CAS Number1629249-40-6
-
Formula Weight524.106
-
Molecular FormulaC29H38ClN5O2
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(O)C[C@@H](C1=CC=CC(N2N=C(C)C=C2C)=C1)CN3C[C@H](CCC4=NC5=C(CCCN5)C=C4)CC3.[H]Cl
-
Chemical Name(S)-3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
RUC-4
A potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors.
-
Gambogic Acid
Gambogic Acid ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1.
-
Gly-Arg-Gly-Asp-Ser
Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.
